Remote-controlled therapeutics,
now nonfiction.

01

Imagine

Therapeutics precisely switched on at tumors, exactly when required, guided by imaging. With this precision, higher drug doses become possible. The result is dramatically improved safety and therapeutic outcomes for patients.
02

What We Do

We’ve created the world’s first strongly magnetically-responsive proteins. With simple, non-invasive magnetic fields, we can remotely activate drugs deep within the body, providing unmatched precision, reversibility, and safety.

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Precision

Targeted drug activity where it’s needed, sparing healthy tissue.

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Control

Activate or deactivate therapeutics remotely in seconds.

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Efficacy

Greatly reduce systemic toxicity, enabling higher safe doses.

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Modularity

Quickly adapt masking to clinically-validated antibodies.

03

Introducing MagBodies

We have created the world’s first magnetically-responsive antibody. By applying a fridge-magnet-strength magnetic field, we can remotely modulate the binding affinity, and therefore potency, of an antibody drug.
key-graph-elisa

Research Library

Hayward et al.

Magnetic control of the brightness of fluorescent proteins


view research
Zenodo 2025

abrahams et al.

Quantum spin resonance in engineered magneto-sensitive fluorescent proteins enables multi-modal sensing in living cells

view research
Biorxiv 2026

burd et al.

Magnetic resonance control of reaction yields through genetically-encoded protein:flavin spin-correlated radicals in a live animal

view research
Biorxiv 2026

xiang et al.

Mechanism of giant magnetic field effect in fluorescence of mScarlet3, a red fluorescent protein

view research
JACS 2026

Would you like to work with
magnetically-responsive proteins?

Reach out to us

Applications

Antibodies & Binders

Magnetically gated antibodies, T-cell engagers, and binding scaffolds for spatially controlled therapeutic targeting.

Targeted Control & Safety

Engage targets precisely at desired sites, eliminating systemic toxicities including CRS.

Clinical translation ready

Mask existing clinically-validated antibodies and other binders to add spatiotemporal control.

Oncology ADCS T-Cell Engagers

CAR-T & Cell Therapies

External spatial control over chimeric antigen receptors and T cell receptor activity.

Spatiotemporal control

CAR-T active only at the tumor, reducing systemic toxicity with reversible on-off activation.

100% genetically encoded

Fully encoded system compatible with in vivo CAR-T delivery and manufacturing.

Oncology Immunotherapy Cell Therapy

Cytokines

Deliver powerful immune modulators like IL-2 without dangerous systemic side effects.

Localized Activation

Powerful cytokine effects confined to target tissue, minimizing toxicity.

Reversible Control

Real-time activation and deactivation enables precise therapeutic windows.

Oncology Immunotherapy IL-2

Genetic Control

Magnetically controlled tools for genome editing, gene expression, optogenetics, and diagnostics.

Precision editing

CRISPR-Cas and transcription factor activity gated by magnetic field presence.

Versatile platforms

Channelrhodopsins, bioluminescent reporters, and reversible capture/separation systems.

Gene Editing Optogenetics Diagnostics

Do you have a drug that would
benefit from our technology?

Reach out to us
04

Our Team

We’ve created the world’s first genetically encoded magnetically-responsive proteins. With simple, non-invasive magnetic fields, we can remotely activate drugs deep within the body, providing unmatched precision, reversibility, and safety.

CEO

Richard 
Fuisz

Richard Fuisz_Headshot

Richard is a co-founder of Nonfiction, where he is developing magnetogenetic tools to enable precise, noninvasive control of protein therapeutics using modest magnetic fields. Richard Fuisz is a co-inventor of several patents, including several related to magnetogenetic control of protein therapeutics. Prior to Nonfiction Labs, Richard founded DNA-synthesis company Templa Nucleics, was a founding team member of Arcadia Science and FutureHouse. Richard received his B.S. in Bioengineering at Stanford University.

CSO

Maria Del Mar Ingaramo

Maria Del Mar Ingaramo_Headshot

Maria is a co-founder of Nonfiction, where she is advancing magnetogenetic control of protein therapeutics using modest (~10 mT) magnetic fields. Prior to Nonfiction, María discovered that fluorescent proteins respond to magnetic fields, and engineered the first large-response magneto-protein, MagLOV. Earlier, she completed her post-doctoral work with George Patterson, building advanced microscopy systems and marrying probe design with cutting-edge imaging.

Scientist

Rebecca Frank Hayward

Rebecca Frank Hayward_Headshot

Rebecca develops next-generation light- and magnetically-controlled proteins, drawing on expertise at the intersection of protein engineering, fluorescence microscopy, and patterned-light stimulation. Prior to Nonfiction Labs, Rebecca built all-optical electrophysiology platforms in Adam Cohen’s laboratory at Harvard and contributed to the discovery of magnetic field control of fluorescent proteins in Andrew York’s laboratory at Calico. Rebecca received her Ph.D. from Harvard University.

Scientist

Regina 
Mencia

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Regina develops magnetically controlled protein systems for precise, noninvasive biological control. Prior to Nonfiction, Regina worked as a postdoctoral researcher at the Max Planck Institute for Biology in Tübingen, Germany, where she brought expertise in gene regulation and molecular engineering as a trained plant epigeneticist. Regina received a dual Ph.D. from Universidad Nacional del Litoral (Argentina) and TU Dresden (Germany).

Scientist

Maria Clara 
Ingaramo

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María Clara works on protein screening systems to support the selection and optimization of MagnetoTherapeutics at Nonfiction. Prior to Nonfiction, María Clara worked on protein function, autophagy, and metabolic regulation using Drosophila as an in vivo model. She gained experience in fluorescent reporter development during research stays at Harvard Medical School (Perrimon lab) and Calico. María Clara received her Ph.D. and completed postdoctoral training at CONICET–UNL in Argentina.

Scientist

Andres 
Dekanty

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Andrés leads laboratory operations for Nonfiction’s Argentina site, overseeing facility build-out, equipment procurement, and local team coordination. His research spans over 20 years in genetics, cellular, and molecular biology. Andrés received his Ph.D. from the Instituto Leloir / Universidad de Buenos Aires and completed postdoctoral training at IRB Barcelona.

Scientist

Paula 
Wagner

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Paula optimizes engineered protein constructs at Nonfiction Labs, leveraging large-scale site-directed mutagenesis to enhance enzymatic magnetogenetic control. Prior to Nonfiction Labs, Paula conducted research as a chronobiologist examining how circadian proteins influence glioblastoma growth, uncovering chronochemotherapy strategies for brain tumors. Paula received her Ph.D. in biotechnology with expertise in circadian biology and cancer metabolism.

Scientist

Pablo Torti

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Pablo designs, produces, and tests magbodies that target novel targets, contributing to the development of Nonfiction’s therapeutic asset pipeline. Prior to Nonfiction Labs, Pablo completed postdoctoral training in protein nanobioengineering at IPROBYQ (CONICET), specializing in recombinant protein design and scale-up. Pablo received his Ph.D. in Biological Sciences from Universidad Nacional del Litoral.

Scientist

Nadia Gonzalez

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Nadia implements and optimizes laboratory techniques at Nonfiction Labs, including protein production and purification, ELISA assays, and technical support across research and development activities. Prior to Nonfiction Labs, Nadia developed expertise in molecular biology, cell culture, and protein engineering through her doctoral research. Nadia received her Ph.D. in Biological Sciences.

Scientist

María Jesús Leopold

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María Jesús designs, produces, and tests magbodies that target novel targets, contributing to the development of Nonfiction’s therapeutic asset pipeline. Prior to Nonfiction Labs, María Jesús worked extensively on therapeutic protein engineering, including expression in mammalian cell systems and monoclonal antibody production, purification, and characterization. María Jesús received her Ph.D. in Biological Sciences from Universidad Nacional del Litoral.

Scientist

Paige Creeks

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Paige screens novel magnetogenetic binders and proteins, scaling our screening capabilities and developing robust manufacturing protocols. Prior to Nonfiction Labs, Paige worked on IgE monoclonal antibody (mAb) discovery, developing novel therapeutic platforms for immune-mediated diseases. Her research background includes extensive work in genetic engineering and protein characterization assays. Paige holds a background in molecular biology with specialization in therapeutic antibody development.

Scientific Advisor

Andrew York

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Andrew advises Nonfiction Labs on imaging techniques and magnetogenetics. Previously, Andrew led a research group at Calico Life Sciences where he co-discovered magnetic field control of fluorescent proteins. Andrew has made significant contributions to the field of magnetogenetics, including the co-discovery of magnetic field control of fluorescent proteins and contributions in optical physics, super-resolution imaging, and light-matter interactions.

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Join Our Team

Group 36

We’re looking for exceptional scientists to help advance magnetogenetic therapeutics.

GET IN TOUCH

hiring

Join Our Team

Group 36

We’re looking for exceptional scientists to help advance magnetogenetic therapeutics.

GET IN TOUCH
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